Methylation Status and Neurodegenerative Markers in Parkinson Disease
نویسندگان
چکیده
منابع مشابه
Methylation status and neurodegenerative markers in Parkinson disease.
BACKGROUND Increased concentrations of plasma total homocysteine (tHcy) have been associated with age-related diseases, including dementia, stroke, and Parkinson disease (PD). Methylation status might link Hcy metabolism to neurodegenerative proteins in patients with PD. METHODS We tested blood samples from 87 patients with PD (median age 68 years; 35 men) for tHcy, methylmalonic acid (MMA), ...
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1 Department of Neuroscience, AFaR-Ospedale “San Giovanni Calibita” Fatebenefratelli, Isola Tiberina, 00186 Rome, Italy 2 Neurodegeneration Laboratory, IRCCS San Raffaele Pisana, 00166 Rome, Italy 3 Department of Neurology, University Hospital Utrecht, 3584 CX Utrecht, The Netherlands 4Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 4810...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2009
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2009.125021